Gene: [06^/ADACF1] adenosine deaminase complexing protein 1; [ADCP1 ]
|
COM |
The GDB and MIM Catalogues accept the code ADCP1 for a protein that form
complexes with ADA. As a result, they are separated from ADA in
the alphabetic list and; furthermore, this contradicts the rule of using
the symbol for pseudogenes. To avoid this, in the HUGEN the code ADACF (ADA Conversion Factor) is accepted." |
|
FAG |
The complex-forming ADCP protein is supposed to have two isoforms, ADCP1 and ADCP2. The latter is mapped to Chr 2 (see GEM:02q243/DPP4). For more information on the functional association with the red blood cell adenosine deaminase, see GEM:20q1311/ADA." |
|
HET |
It is possible that some forms of 'combined immunodeficiency' associated with the ADA deficiency (VanCong-1981) are actually accounted for by the ADCP protein alterations." |
|
REF |
IDN,FUN,LOC "Daddona, Kelley: BBA, 580, 302-311, 1979 IDN,FUN,LOC "Koch G, Shows: PNAS, 75, 3876-3880, 1978 HET,PAT "VanCong &: Ann Genet, 24, 141-147, 1981 |
|
KEY |
hem, imm |
|
CLA |
unknown, basic |
|
LOC |
06 |
|
MIM |
MIM: 102710 |
|
SYN |
ADCP1 |
